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WAVE Bioreactor Systems

WAVE single use bioreactors were developed by WAVE Biotech in 1996 and led the revolution in single use technologies that is redefining upstream and downstream processing of biopharmaceuticals today. The bioreactor requires no cleaning or sterilization, providing the ultimate ease of operation and protections against cross contamination.

In the WAVE Bioreactor system cell culture medium and cells contact only a presterile, disposable chamber, the Cellbag, that is placed on a special rocking platform. The rocking motion of this platform induces waves in the cell culture fluid. These waves provide mixing and oxygen transfer, resulting in a perfect environment for cell growth that can easily support over 10 x 106 cells/ml.

WAVE Bioreactor systems support the ReadyToProcess platform of ready for use products used in the upstream and downstream processing of biopharmaceuticals. WAVE Bioreactors are also used for cell expansion in applications within gene and cell therapy, and regenerative medicine.


Cell Culture Products

WAVE Bioreactor™ is a cell culture device suitable for applications in animal, virus, insect, and plant cell culture in suspension, or on microcarriers, as well as cellular therapeutics.

Disposable cell culture systems for 0.1 to 500 liters.
Thousands of units in use worldwide.
Culture medium and cells only contact a presterile, disposable chamber called a Cellbag.
Cellbag rests on a specifically designed rocking platform that induces waves in the culture fluid.
These waves provide mixing and oxygen transfer, resulting in a perfect environment for cell growth.
No cleaning or sterilization needed.
 

Cellbag™ is a truly Custom Bioreactor. Add a filter, quick connect fitting or 10 feet of tubing - you decide!

Disposable bioreactors are available in standard formats or are easily customized.
For research, development or cGMP manufacturing operations.
Flexible packaging products to meet your needs.
 


Mixing Products

WAVE Mixer™ provides efficient mixing in a sealed bag by using the wave induction approach.

No pump or impeller to induce circulation flow, uses waves generated by rocking motion.
Wave motion moves large volumes of fluid and disperses solids.
Very efficient at generating waves because it essentially uses gravity to accelerate the wave.
 


Fluid Transfer Products

Sterile Tube Fuser is ideal for the aseptic transfer of inoculums, media, buffers, or process intermediates.

Welds a variety of types and sizes of thermoplastic tubing.
True thermal weld provides exceptional strength.
Aseptic connections without a laminar hood.
User-programmable, PC interface for data printing and parameter download.
PTFE-coated blades to ensure strong, reliable welds.
 

Hot Lips Tube Sealer™ is a portable device used to thermally seal thermoplastic tubing.

Seals 0.25 to 1.25 inch OD thermoplastic tubing.
For PharMed®, C-Flex®, PVC or similar tubing.
True thermal seal provides tamperproof protection.
Compact, ultra portable 18 lb machine.
No compressed air or cooling water needed.
Automated validatable 2-3 minute sealing cycle.